Antioxidant Activity of Croton zambesicus Muell. Arg Seed Extract
Asian Journal of Research in Biochemistry,
Page 1-5
DOI:
10.9734/ajrb/2022/v11i3-4216
Abstract
The present study was designed to investigate the antioxidant activity of Croton zambesicus Muell. Arg seed extract and fractions (Family: Euphorbiaceae). The antioxidant property was assessed by testing for DPPH free radical scavenging activity. Potential antioxidant activity was presented by methanolic extract. C. zambesicus showed high DPPH value (83.21 ± 0.05). Crude extract was fractionated using separation funnel, the five fractions were obtained are hexane, chloroform, ethyl acetate, n-butanol and water which represented antioxidant activities equal to 46.2 ± 0.1349, 45.1 ± 0.0116, 49.9 ± 0.0337, 40.45 ± 0.2290 and 62.7 ± 0.0006 respectively.
Keywords:
- Croton zambesicus
- antioxidant activity
- separation funnel
How to Cite
Ibrahim, M. A., Fadlalla, D. E., Elkhalifa, H. E., Ahmed, M. E., & Ahmed, S. B. (2022). Antioxidant Activity of Croton zambesicus Muell. Arg Seed Extract. Asian Journal of Research in Biochemistry, 11(3-4), 1-5. https://doi.org/10.9734/ajrb/2022/v11i3-4216
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Azaizah H, Fulder SK, Said K, O. Ethnobotanical Knowledge of local Arab practitioners in the Middle Eastern region Fitoter. 2003;74:98-108.
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Okokon JE, Ofodum KC, Ajibesin KK, Danladi B, Gamaniel KS. Pharmacological screening and evaluation of anti-plasmodial activity of Croton zambesicus against plasmodium berghei-berghei infection in mice. Indian J Pharmacol. 2005;37(4):243-6.
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Abdallah EM. Plants: an alternative source for antimicrobials. J Appl Pharm Sci. 2011;1(6):16-20.
Sukanya SL, Sudisha J, Hariprasad P, Niranjana SR, Prakash HS, Fathima SK. Antimicrobial activity of leaf extracts of Indian medicinal plants against clinical and phytopathogenic bacteria. Afr J Biogr. 2009;8(23):6677-82.
Cai Y, Luo Q, Sun M, Corke H. Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Sci. 2004;74(17):2157-84.
DOI: 10.1016/j.lfs.2003.09.047, PMID 14969719.
WHO. Legal status of traditional medicine and complementary alternative medicine: A Worldwide Review. Geneva: World Health Organization; 2001.
Maria V, Sulistyo E, Dwi P, Maria G, Marianti P. Antioxidant and toxicity activity of aqueous extracts from various parts of breadfruit and breadnutYoanes. Int J Fruit Sci. 2020;20(3):1639-165.
Saeed N, Khan MR, Shabbir M. Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L. B.M.C. Complement Altern Med. 2012;12(1):221.
DOI: 10.1186/1472-6882-12-221, PMID 23153304.
El-Hamidi A. Drug plants of the Sudan Republic in native medicine. Plant. Med. 1970;18:278-80.
Ngadjui BT, Folefoc GG, Keumedjio F, Dongo E, Sondengam BL, Connolly JD. Crotonadiol, a labdane diterpenoid from the stem bark of Croton zambesicus. Phytochemistry. 1999;51(1):171-4.
DOI: 10.1016/S0031-9422(98)00706-7
Okokon JE, Nwafor PA. Antiplasmodial activity of root extract and fractions of Croton zambesicus. J Ethnopharmacol. 2009;121(1):74-8.
DOI: 10.1016/j.jep.2008.09.034, PMID 18996464.
Okokon JE, Bassey AL, Obot J. Antidiabetic activity of ethanolic leaf extract of Croton zambesicus on alloxan diabetic rats. Afr J Tradit Complement Altern Med. 2006;31:21-6.
El Kamali HH, Khalid SA. The most common herbal remedies in Central Sudan. Fitoterapia. 1996;68:301-6.
Shimada K, Fujikawa K, Yahara K, Nakamura T. Antioxidative properties of xanthan on the autoxidation of soybean oil in cyclodextrin emulsion. J Agric Food Chem. 1992;40(6):945-8.
DOI: 10.1021/jf00018a005
Ibrahim MA, Ali AM, Maky MA, Abas NN, Hassan SH. Antimicrobial and antioxidant activity of seed extracts of Croton zambesicus Muell. Arg. Sch. App J. Med Sci. 2015;3(7C):2665-7.
Ofentse M, Kabo W, Tebogo EK, Shetonde OM, Bokolo MK. Cinnamomum verum:ethyl acetate and methanol extracts antioxidant and antimicrobial activity. J Med Plants Stud. 2015;3(3):28-32.
Huang D, Ou B, Prior RL. Of the chemistry behind antioxidant capacity assays. J Agric Food Chem. 2005;53(6):1841-56.
DOI: 10.1021/jf030723c,
PMID 15769103.
Hassan LEA, Dahham SS, B.M.C. Complement Altern Med. M., Mohammed AMA, Majis, AMSA, Majid ASA. Chemotherapeutic potentials of the stem bark of Balanites aegyptiaca (L.) Delile: An antiangiogenic, antitumor and antioxidant agent. 2016;16:396.
Mohamed NA, Ali A, Ahmed SK. In vitro antioxidant activity and phytochemical screening of Croton zambesicu. J Pharmacogn Phytochem. 2016;5(6): 12-6.
Azaizah H, Fulder SK, Said K, O. Ethnobotanical Knowledge of local Arab practitioners in the Middle Eastern region Fitoter. 2003;74:98-108.
Ali HibaA, Elamin H, Hamza A. Phytochemical profiling, antimicrobial Activity and brine shrimps lethality of Croton zambesicus seeds and leaves extracts. J Biol; 2017.
Okokon JE, Ofodum KC, Ajibesin KK, Danladi B, Gamaniel KS. Pharmacological screening and evaluation of anti-plasmodial activity of Croton zambesicus against plasmodium berghei-berghei infection in mice. Indian J Pharmacol. 2005;37(4):243-6.
DOI: 10.4103/0253-7613.16571
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