Antifungal Action of Garlic (Allium sativum) and Ginger (Zingiber officinale) on Some Pathogenic Fungi
Asian Journal of Research in Biochemistry,
Background: The antifungal activities of fresh garlic (Allium sativum) and ginger (Zingiber officinale) on the growth of three known pathogenic fungi were investigated. The test organisms were Aspergillus spp Penicillium spp and Candida albicans.
Methodology: Two different concentrations of extracts were used. Concentration I which had crude extract of 100 g/ 100 ml of sterile distilled water and concentration II with extract of 100 g/50 m1 of distilled water. Ten mls of each extract was added to each 125 m1 of SAB (saboraud dextrose agar) media before and after sterilization.
Results: The extracts added to the media after its sterilization inhibited the growth of the pathogenic fungi samples more than the extracts added to the media before sterilization. This indicates that the active ingredients present in the extracts which have the antifungal effect observed is negatively affected and inactivated at 121ºC for 15 minutes. It can be inferred that garlic and ginger have different levels of therapeutic values on fungi.
- pathogenic fungi
How to Cite
Amonkar SV, Banerji A. Isolation and characterization of Larvicidal principle of garlic. Science. 1971;174(16):1343-1344.
Barone FE, Tansey MR. Isolation, purification, identification, synthesis and kinetics of activity of the anticandidal component of Allium sativurn, arid a hypothesis for its mode of action. Myco-logia. 1977;69(4):793- 825.
Panthee DR, Kc RB, Regmi HN, Subedi PP, Bhattarai S, Dhakal J. Diversity analysis of garlic (Allium sativum L.) germ-plasms available in Nepal based on morphological characters. Genetic Resources and Crop Evolution. 2006; 53(1):205-212.
Kafaru E. The different uses of Garlic. Herbal remedies, The Guardian. 1997. 1994;12.
George D. Pamplona-Roger. Encyc-lopedia of medicinal herbs 1. Education and Health Library, Editorial Safeliz SL. Aravaca, 8/28040 Madrid (Spain). 1998; 230-377.
Chuku EC, Osakwe JA, Daddy-West C. Fungal spoilage of tomato (Lycopersicone esculentum Mill) and control using ginger and garlic. Scientia Africana. 2010;9(2):41-49.
Singh G, Kapoor IP, Singh P, de Heluani CS, de Lampasona MP, Catalan CA. Chemistry, antioxidant and antimicrobial investigations on essential oil and oleoresins of Zingiber officinale. Food Chem. Toxicol. 2008;46:3295–3302.
Wachukwu CK, Sokari TG, Amadi AG. Antibacterial activity and deodorization of garlic Allium sativum. Journal of Applied Science and Environmental Management. 1999;2:35-37.
Bailey JH, Cavallito CJ. Allium: The antibacterial principle of Allium sativum. In: Isolation, chemical properties arid anti-bacterial action. Journal of American Chemical Society. 1944;64(1):1950-195.
Indries TH. Chemical composition of Ginger. American Journal of Pharmaco-logy. 1998;26:466-468.
Fawett W. History and description of ginger. American Journal of Pharmacology. 1994;24:533-593.
AOAC. Association of official analytical chemists, Washington D.C. 1990;122-210.
Cheesebrough MJ. Medical laboratory manual for tropical health technology and butter-worth scientific publication, Boston. 1991;167-214.
Olds RJ. A colour atlas of microbiology, 5th Edition. Wolf Medical Publication Ltd. London. 1983;102.
Banerjee SK, Maulik SK. Effect of garlic on cardiovascular disorders: A review. Nutrition Journal. 2002;1(1):4.
Benavides GA, Squadrito GL, Mills RW, Patel HD, Isbell TS, Patel RP, Victor MD, Jeannette ED, Kraus DW. Hydrogen sulfide mediates the vaso activity of garlic. Proceedings of the National Academy of Sciences. 2007;104(46):17977-17982.
Hsing AW, Chokkalingam AP, Gao YT, Madigan MP, Deng J, Gridley G, Fraumeni Jr. JF. Allium vegetables and risk of prostate cancer: A population-based study. Journal of the National Cancer Institute. 2002;94(21):1648-1651.
Fukao H, Yoshida H, Tazawa YI, Hada T. Antithrombotic effects of odorless garlic powder both in vitro and in vivo. Bio-science, Biotechnology, and Biochemistry. 2007;0612070194-0612070194.
Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins, Leuko-trienes and Essential Fatty Acids. 1997; 56(5):379-384.
Chauhan NB. Effect of aged garlic extract on APP processing and tau phosphory-lation in Alzheimer's transgenic model Tg2576. Journal of Ethnopharmaco-logy. 2006;108(3):385-394.
Tagoe DNA, Nyarko HD, Akpaka R. A comparison of the antifungal properties of onion (Allium cepa), ginger (Zingiber officinale) and garlic (Allium sativum) against Aspergillus flavus, Aspergillus niger and Cladosporium herbarum. Journal of Medical Plant Research. 2011;5:281-287.
Bellik Y. Total antioxidant activity and antimicrobial potency of the essential oil and oleoresin of Zingiber officinale roscoe. Asian Pacific. Journal of Tropical Diseases. 2014;4:40–44.
Yetgin A, Canlı K, Altuner EM. Comparison of antimicrobial activity of Allium sativum cloves from China and Taşköprü, Turkey. Advances in Pharmacological Sciences; 2018.
Abstract View: 2317 times
PDF Download: 1115 times